The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2011
Filed:
Oct. 19, 2005
Michael J. Sailor, La Jolla, CA (US);
Michael P. Schwartz, Boulder, CO (US);
Sara Alvarez, Oceanside, CA (US);
Sangeeta Bhatia, Lexington, MA (US);
Austin Derfus, San Diego, CA (US);
Benjamin Migliori, La Jolla, CA (US);
Lin Chao, Del Mar, CA (US);
Yang Yang LI, Irvine, CA (US);
Rebecca Campbell, La Jolla, CA (US);
Jason Dorvee, Ithaca, NY (US);
Ulla Camilla Rang, Del Mar, CA (US);
Michael J. Sailor, La Jolla, CA (US);
Michael P. Schwartz, Boulder, CO (US);
Sara Alvarez, Oceanside, CA (US);
Sangeeta Bhatia, Lexington, MA (US);
Austin Derfus, San Diego, CA (US);
Benjamin Migliori, La Jolla, CA (US);
Lin Chao, Del Mar, CA (US);
Yang Yang Li, Irvine, CA (US);
Rebecca Campbell, La Jolla, CA (US);
Jason Dorvee, Ithaca, NY (US);
Ulla Camilla Rang, Del Mar, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
The invention includes sensors and sensing methods for determining cell morphology and/or chemical composition of an analyte. A porous substrate exhibiting a first optical signal is exposed to a target analyte and subsequently monitored for changes in the optical signal. More specifically, a photonic or porous substrate having a well-defined and highly tunable reflectivity or transmission spectrum, such as porous silicon (Si), porous alumina, porous Ge, porous GaAs, porous SiO2 and porous polymer, is used for example. A porous or photonic substrate is exposed to an analyte, such as a cell or other macromolecule, and changes in the scattered light are observed over time to determine cell morphology and/or chemical composition of the analyte using the substrate.