The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2011
Filed:
Nov. 17, 2006
Juan Jose Artus Surroca, Vilanova i la Geltrú, ES;
David Fernandez Bleda, Castelldefels, ES;
Tommaso Iacoangeli, Rome, IT;
Jordi Lluis Tous, Tarragona, ES;
Juan Jose Artus Surroca, Vilanova i la Geltrú, ES;
David Fernandez Bleda, Castelldefels, ES;
Tommaso Iacoangeli, Rome, IT;
Jordi Lluis Tous, Tarragona, ES;
Sinclair Pharmaceuticals Limited, Surrey, GB;
Abstract
A process for the preparation of delmopinol (3-(4-propylheptyl)-4-morpholinethanol) or a derivative or a pharmaceutically acceptable salt, or a solvate thereof, including an hydrate, comprises reacting oxazolidin [2, 3-c] morpholine and a grignard reagent, and optionally converting the delmopinol (or derivative) free base into a pharmaceutically acceptable salt. The oxazolidin [2, 3-c] morpholine and the grignard reagent are useful as intermediates in the production process.