The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2011

Filed:

Aug. 22, 2008
Applicants:

Irina Neagu, Plainsboro, NJ (US);

David Diller, East Windsor, NJ (US);

Celia Kingsbury, Cream Ridge, NJ (US);

Adolph C. Bohnstedt, Burlington, NJ (US);

Michael J. Ohlmeyer, Plainsboro, NJ (US);

Vidyadhar Paradkar, Somerville, NJ (US);

Nasrin Ansari, Monmouth Junction, NJ (US);

Inventors:

Irina Neagu, Plainsboro, NJ (US);

David Diller, East Windsor, NJ (US);

Celia Kingsbury, Cream Ridge, NJ (US);

Adolph C. Bohnstedt, Burlington, NJ (US);

Michael J. Ohlmeyer, Plainsboro, NJ (US);

Vidyadhar Paradkar, Somerville, NJ (US);

Nasrin Ansari, Monmouth Junction, NJ (US);

Assignee:

Wyeth LLC, Madison, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/32 (2006.01); C07D 473/18 (2006.01); A61K 31/52 (2006.01); A61K 31/522 (2006.01); A61P 37/06 (2006.01); A61P 11/06 (2006.01); A61P 35/02 (2006.01); C07D 239/48 (2006.01); C07D 239/50 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides novel purinones and purines useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection. The compounds are of the general formulae I and II shown below, in which Q is selected from the group consisting of CX and nitrogen; and A is chosen from the group consisting of H, (C-C) alkyl, heteroaryl, and aryl:


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