The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2011

Filed:

May. 09, 2007
Applicants:

Jukka T. Salonen, Kuopio, FI;

Jelena Hyppönen, Kuopio, FI;

Jari Kaikkonen, Kuopio, FI;

Mia Pirskanen, Kuopio, FI;

Pekka Uimari, Kuopio, FI;

Juha-matti Aalto, Siilinjärvi, FI;

Inventors:

Jukka T. Salonen, Kuopio, FI;

Jelena Hyppönen, Kuopio, FI;

Jari Kaikkonen, Kuopio, FI;

Mia Pirskanen, Kuopio, FI;

Pekka Uimari, Kuopio, FI;

Juha-Matti Aalto, Siilinjärvi, FI;

Assignee:

DSM IP Assets B.V., Heerlen, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

Genes, SNP markers and haplotypes of susceptibility or predisposition to T2D and subdiagnosis of T2D and related medical conditions are disclosed. Methods for diagnosis, prediction of clinical course and efficacy of treatments for T2D, obesity and related phenotypes using polymorphisms in the risk genes are also disclosed. The genes, gene products and agents of the invention are also useful for monitoring the effectiveness of prevention and treatment of T2D and related traits. Kits are also provided for the diagnosis, selecting treatment and assessing prognosis of T2D. Novel methods for prevention and treatment of metabolic diseases such as T2D based on the disclosed T2D genes, polypeptides and related pathways are also disclosed.


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