The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2011
Filed:
Dec. 03, 2003
Shan LU, Franklin, MA (US);
Shixia Wang, Northborough, MA (US);
Ranajit Pal, Gaithersburg, MD (US);
Vaniambadi Kalyanaraman, Rockville, MD (US);
Stephen Charles Whitney, Silver Spring, MD (US);
Tim Keen, Silver Spring, MD (US);
Balachandran Nair, Gaithersburg, MD (US);
Phillip Markham, Mount Airy, MD (US);
Shan Lu, Franklin, MA (US);
Shixia Wang, Northborough, MA (US);
Ranajit Pal, Gaithersburg, MD (US);
Vaniambadi Kalyanaraman, Rockville, MD (US);
Stephen Charles Whitney, Silver Spring, MD (US);
Tim Keen, Silver Spring, MD (US);
Balachandran Nair, Gaithersburg, MD (US);
Phillip Markham, Mount Airy, MD (US);
University of Massachusetts, Boston, MA (US);
Advanced Bioscience Laboratories, Kensington, MD (US);
Abstract
Polyvalent, primary isolate nucleic acid compositions for inducing an immune response against HIV is disclosed. The composition and methods described herein are for the use of a DNA composition that encodes one or more different HIV envelope glycoproteins. The DNA composition can encode an HIV Gag protein. The DNAs encoding one or more HIV proteins are a combination of different nucleic acids, such as DNA plasmids, generated from primary isolate DNA of different HIV major group genetic clades and/or different proteins. HIV protein compositions for inducing an immune response against HIV are disclosed. Methods fro using the protein compositions as boosts following administration of the DNA compositions are provided.