The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2011

Filed:

Feb. 21, 2007
Applicants:

David Matthew Marquis, Encinitas, CA (US);

Eric Michael Smith, San Diego, CA (US);

Danise Rogers Subramaniam, Zionsville, IN (US);

Derrick Ryan Witcher, Fishers, IN (US);

Inventors:

David Matthew Marquis, Encinitas, CA (US);

Eric Michael Smith, San Diego, CA (US);

Danise Rogers Subramaniam, Zionsville, IN (US);

Derrick Ryan Witcher, Fishers, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 21/08 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are humanized monoclonal antibodies, and antigen-binding portions thereof, which bind acylated and unacylated human ghrelin. Such antibodies are useful for neutralizing ghrelin activity and treating disorders in which ghrelin activity is detrimental, including obesity and related disorders, and various cancers.


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