The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2011

Filed:

Oct. 24, 2007
Applicants:

Stephan Schilling, Halle/Saale, DE;

Mirko Buchholz, Halle/Saale, DE;

Andre Niestroj, Sennewitz, DE;

Ulrich Heiser, Halle/Saale, DE;

Hans-ulrich Demuth, Halle/Saale, DE;

Inventors:

Stephan Schilling, Halle/Saale, DE;

Mirko Buchholz, Halle/Saale, DE;

Andre Niestroj, Sennewitz, DE;

Ulrich Heiser, Halle/Saale, DE;

Hans-Ulrich Demuth, Halle/Saale, DE;

Assignee:

Probiodrug AG, Halle-Saale, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/417 (2006.01); A61K 31/4164 (2006.01); C07D 233/61 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel inhibitors of glutaminyl cyclase and combinations thereof for the treatment of neuronal disorders, especially Alzheimer's disease, Down Syndrome, Parkinson disease, Chorea Huntington, pathogenic psychotic conditions, schizophrenia, impaired food intake, sleep-wakefulness, impaired homeostatic regulation of energy metabolism, impaired autonomic function, impaired hormonal balance, impaired regulation, body fluids, hypertension, fever, sleep dysregulation, anorexia, anxiety related disorders including depression, seizures including epilepsy, drug withdrawal and alcoholism, neurodegenerative disorders including cognitive dysfunction and dementia.


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