The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2011

Filed:

Jul. 16, 2008
Applicants:

Qingping Zeng, Thousand Oaks, CA (US);

Dawei Zhang, Thousand Oaks, CA (US);

Guomin Yao, Newbury Park, CA (US);

George E. Wohlhieter, Lake Balboa, CA (US);

Xianghong Wang, Moorpark, CA (US);

James Rider, Woodland Hills, CA (US);

Andreas Reichelt, Moorpark, CA (US);

Holger Monenschein, Camarillo, CA (US);

Fang-tsao Hong, Thousand Oaks, CA (US);

James R. Falsey, Moorpark, CA (US);

Celia Dominguez, Los Angeles, CA (US);

Matthew P. Bourbeau, Woodland Hills, CA (US);

John G. Allen, Newbury Park, CA (US);

Inventors:

Qingping Zeng, Thousand Oaks, CA (US);

Dawei Zhang, Thousand Oaks, CA (US);

Guomin Yao, Newbury Park, CA (US);

George E. Wohlhieter, Lake Balboa, CA (US);

Xianghong Wang, Moorpark, CA (US);

James Rider, Woodland Hills, CA (US);

Andreas Reichelt, Moorpark, CA (US);

Holger Monenschein, Camarillo, CA (US);

Fang-Tsao Hong, Thousand Oaks, CA (US);

James R. Falsey, Moorpark, CA (US);

Celia Dominguez, Los Angeles, CA (US);

Matthew P. Bourbeau, Woodland Hills, CA (US);

John G. Allen, Newbury Park, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); A61K 31/416 (2006.01); C07D 217/02 (2006.01); C07D 231/56 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to heterocyclic compounds of Formula I and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.


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