The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7897613 B1

PDF
Full Text
Expired
Date of Patent:
Mar. 01, 2011

Filed:

Sep. 09, 2004
Applicants:

Ramakrishnan Arul, Maharashtra, IN;

Ajay Singh Rawat, Maharashtra, IN;

Maheshkumar Gadakar, Maharashtra, IN;

Rajesh Rao, Maharashtra, IN;

Abhinay Pise, Maharashtra, IN;

Jason Gray, Hertfordshire, GB;

Inventors:

Ramakrishnan Arul, Maharashtra, IN;

Ajay Singh Rawat, Maharashtra, IN;

Maheshkumar Gadakar, Maharashtra, IN;

Rajesh Rao, Maharashtra, IN;

Abhinay Pise, Maharashtra, IN;

Jason Gray, Hertfordshire, GB;

Assignee:

Generics [UK] Limited, Potters Bar, Hertfordshire, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61K 31/4365 (2006.01); A61P 7/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel crystalline forms of the platelet aggregation inhibitor (+)-(S)-methyl-2-(2-chlorophenyl)-(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate, clopidogrel (1), in the form of hydrogen bromide salts, identified as polymorph forms 1, 2 and 3. The present invention further relates to processes for preparing such forms, pharmaceutical compositions comprising such forms, and uses for such forms and compositions. The pharmaceutical compositions may be used, in particular, for inhibiting platelet aggregation or for treating, preventing or managing thrombosis, atherothrombosis, an atherothrombotic event, ischaemic stroke, myocardial infarction, non-Q-wave myocardial infarction, atherosclerosis, peripheral arterial disease, or unstable angina. The present invention also relates to methods of treating said disorders. Formula (1).


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