The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2011
Filed:
Apr. 07, 2008
Applicant:
Nazarius Saah Lamango, Tallahassee, FL (US);
Inventor:
Nazarius Saah Lamango, Tallahassee, FL (US);
Assignee:
Florida Agricultural and Mechanical University, Tallahassee, FL (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); C07F 9/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
Inhibitors of the enzyme prenylated methylated protein methyl esterase (PMPMEase), the last step in the prenylation process for many eukaryotic proteins, having the general structure R-X-A-B(R)-Y or R-X-A(R)-B-Y, where Ris preferably a polyisoprenyl group, X is a linking group, Y is a group that promotes affinity interactions to the active site of PMPMEase and imparts hydrolysis resistance to the inhibitor, A and B are bridge atoms, and Ris a characteristic-providing substituent.