The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2011

Filed:

Jun. 16, 2009
Applicants:

Stephan Georg Mueller, Warthausen, DE;

Klaus Rudolf, Warthausen, DE;

Philipp Lustenberger, Basel, CH;

Dirk Stenkamp, Biberach, DE;

Marco Santagostino, Mittelbiberach, DE;

Fabio Paleari, Monza, IT;

Henri Doods, Warthausen, DE;

Kirsten Arndt, Biberach, DE;

Gerhard Schaenzle, Biberach, DE;

Inventors:

Stephan Georg Mueller, Warthausen, DE;

Klaus Rudolf, Warthausen, DE;

Philipp Lustenberger, Basel, CH;

Dirk Stenkamp, Biberach, DE;

Marco Santagostino, Mittelbiberach, DE;

Fabio Paleari, Monza, IT;

Henri Doods, Warthausen, DE;

Kirsten Arndt, Biberach, DE;

Gerhard Schaenzle, Biberach, DE;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/45 (2006.01); A61P 25/06 (2006.01); A61P 5/50 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to the CGRP-antagonists of general formula I wherein R, R, Rand Rare defined as in claim, the tautomers, the isomers, the diastereomers, the enantiomers, the hydrates thereof, the mixtures thereof and the salts thereof and the hydrates of the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, as well as those compounds of general formula I wherein one or more hydrogen atoms are replaced by deuterium, pharmaceutical compositions containing these compounds, their use and processes for preparing them.


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