The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2011

Filed:

Aug. 20, 2007
Applicants:

Gary J. Bridger, Bellingham, WA (US);

Michael J. Abrams, Custer, WA (US);

Geoffrey W. Henson, Ferndale, WA (US);

Ronald Trevor Macfarland, Vancouver, CA;

Gary B. Calandra, Cresco, PA (US);

Hal E. Broxmeyer, Indianapolis, IN (US);

David C. Dale, Seattle, WA (US);

Inventors:

Gary J. Bridger, Bellingham, WA (US);

Michael J. Abrams, Custer, WA (US);

Geoffrey W. Henson, Ferndale, WA (US);

Ronald Trevor MacFarland, Vancouver, CA;

Gary B. Calandra, Cresco, PA (US);

Hal E. Broxmeyer, Indianapolis, IN (US);

David C. Dale, Seattle, WA (US);

Assignee:

Genzyme Corporation, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/33 (2006.01); C07D 245/00 (2006.01); C07D 487/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed. Preferred embodiments of such compounds are of the formulaZ-linker-Z'  (1)


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