The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2011

Filed:

Aug. 26, 2001
Applicants:

Eva Hoess, Munich, DE;

Herbert Andres, Penzberg, DE;

Frederic Donie, Penzberg, DE;

Rudolf Vogel, Weilheim, DE;

Hans-peter Josel, Weilheim, DE;

Rupert Hermann, Weilheim, DE;

Herbert Von Der Eltz, Weilheim, DE;

Inventors:

Eva Hoess, Munich, DE;

Herbert Andres, Penzberg, DE;

Frederic Donie, Penzberg, DE;

Rudolf Vogel, Weilheim, DE;

Hans-Peter Josel, Weilheim, DE;

Rupert Hermann, Weilheim, DE;

Herbert Von Der Eltz, Weilheim, DE;

Assignee:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to a process for the production of a biomolecule-linker conjugate of uniform stochiometry. It especially relates to a conjugate consisting of a biomolecule of a molecular weight between 5 kD and 500 kD and a hydrophilic linker molecule said linker having a molecular weight between 1 and 15 kD and between 4 and 60 charged residues, characterized in that said conjugate comprises at least one biomolecule-linker product of uniform stoichiometry in a pre-selected amount.


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