The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2011

Filed:

Oct. 23, 2008
Applicants:

Anthony J. Kinney, Wilmington, DE (US);

Kimberly F. Glassman, Ankeny, IA (US);

William James Gordon-kamm, Urbandale, IA (US);

Keith S. Lowe, Johnston, IA (US);

Scott E. Nichols, West Chester, PA (US);

Kevin L. Stecca, Bear, DE (US);

Inventors:

Anthony J. Kinney, Wilmington, DE (US);

Kimberly F. Glassman, Ankeny, IA (US);

William James Gordon-Kamm, Urbandale, IA (US);

Keith S. Lowe, Johnston, IA (US);

Scott E. Nichols, West Chester, PA (US);

Kevin L. Stecca, Bear, DE (US);

Assignees:

E. I. du Pont de Nemours and Company, Wilmington, DE (US);

Pioneer Hi-Bred International, Johnston, IA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract

Recombinant constructs useful for reducing the expression of endogenous mRNA and any substantially similar endogenous mRNA are disclosed. In particular, a recombinant construct comprising, inter alia, a suitable nucleic acid sequence and its reverse complement can be used to alter the expression of any homologous, endogenous RNA (i.e., the target RNA) which is in proximity to this suitable nucleic acid sequence.


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