The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2011

Filed:

Aug. 10, 2006
Applicants:

Mehul Patel, Ambler, PA (US);

Dawn M. Schmidt, Durham, NC (US);

Sara H. Thrall, Collegeville, PA (US);

David G. Tew, Harlow Essex, GB;

Inventors:

Mehul Patel, Ambler, PA (US);

Dawn M. Schmidt, Durham, NC (US);

Sara H. Thrall, Collegeville, PA (US);

David G. Tew, Harlow Essex, GB;

Assignee:

AB Sciex, LLC, Framingham, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for characterizing a biochemical reaction and analysis of reaction products by establishing continuously variable concentration gradients of one or more reagents of the biochemical reaction are provided. Methods for determining mechanism of inhibition or activation, potency of inhibition or activation, or both of an enzyme inhibitor or activator, respectively, are also provided. The continuously variable concentration gradients can be established in a microfluidic chip.


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