The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2011

Filed:

Sep. 07, 2007
Applicants:

Vanitha Ramakrishnan, Belmont, CA (US);

David Powers, Fairfax, CA (US);

Dale E. Johnson, Emeryville, CA (US);

Ursula Jeffry, Redwood City, CA (US);

Vinay Bhaskar, San Francisco, CA (US);

Inventors:

Vanitha Ramakrishnan, Belmont, CA (US);

David Powers, Fairfax, CA (US);

Dale E. Johnson, Emeryville, CA (US);

Ursula Jeffry, Redwood City, CA (US);

Vinay Bhaskar, San Francisco, CA (US);

Assignee:

Abbott Biotherapeutics Corp., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); A61K 39/395 (2006.01); A61P 43/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides chimeric and humanized antibodies that specifically recognize α5β1 integrin, and methods for using the antibodies for reducing or inhibiting angiogenesis in a tissue. Also provided are methods of determining therapeutically acceptable doses of the antibodies and pharmaceutical compositions including the same.


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