The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2011
Filed:
Jul. 18, 2006
Christophe Pierre Alain Chassaing, Ingelheim am Rhein, DE;
Christophe Pierre Alain Chassaing, Ingelheim am Rhein, DE;
Intervet International B.V., Boxmeer, NL;
Abstract
This invention relates to benzimidazole carbamates and (thio)carbamates corresponding to Formula I: Here, Xand Xare independently O or S, wherein at least one of Xand Xis O; Yand Yare independently O or S, wherein at least one of Yand Yis O; Ris alkyl having from 1-4 carbon atoms; R, R, and Rare independently hydrogen or a cation; Rand Rare independently hydrogen, halogen, alkyl (having from 1-8 carbon atoms), —OR, —SR, —CO—R, —OSO—Ar, or —S(O)R; Ris alkyl having from 1-8 carbon atoms; Ris alkyl (having from 1-8 carbon atoms) or aryl; Ris alkyl (having from 1-8 carbon atoms), cycloalkyl (having from 3-6 carbon atoms), or aryl; Ar is aryl; and Ris alkyl (having from 1-8 carbon atoms) or aryl. The compounds generally are soluble and stable in water, and have antiparasitic (particularly anthelmintic) activity in vivo that is comparable to known water-insoluble benzimidazole carbamates (e.g., albendazole and fenbendazole).