The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 22, 2011

Filed:

Mar. 14, 2006
Applicants:

Adnan M. M. Mjalli, Oak Ridge, NC (US);

David Jones, Milford, OH (US);

Devi Reddy Gohimmukkula, Jamestown, NC (US);

Guoxiang Huang, Kernersville, NC (US);

Jeff Zhu, High Point, NC (US);

Mohan Rao, Greensboro, NC (US);

Robert C. Andrews, Jamestown, NC (US);

Tan Ren, Colfax, NC (US);

Inventors:

Adnan M. M. Mjalli, Oak Ridge, NC (US);

David Jones, Milford, OH (US);

Devi Reddy Gohimmukkula, Jamestown, NC (US);

Guoxiang Huang, Kernersville, NC (US);

Jeff Zhu, High Point, NC (US);

Mohan Rao, Greensboro, NC (US);

Robert C. Andrews, Jamestown, NC (US);

Tan Ren, Colfax, NC (US);

Assignee:

High Point Pharmaceuticals, LLC, High Point, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/12 (2006.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to benzazole compounds that inhibit β-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment or prevention of diseases in which BACE is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which BACE is involved.


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