The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 22, 2011

Filed:

Mar. 28, 2005
Applicants:

Kevin G. Pinney, Woodway, TX (US);

Maria Graciela Miranda, Waco, TX (US);

James Michael Dorsey, Durham, NC (US);

Inventors:

Kevin G. Pinney, Woodway, TX (US);

Maria Graciela Miranda, Waco, TX (US);

James Michael Dorsey, Durham, NC (US);

Assignee:

Baylor University, Waco, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 239/02 (2006.01); C07D 295/00 (2006.01); C07D 211/30 (2006.01); C07D 211/32 (2006.01);
U.S. Cl.
CPC ...
Abstract

A serotonin reuptake inhibitor which can be used in the treatment of depression and which has a decreased occurrence of unwanted side effects. The serotonin reuptake inhibitors are bi-functional organic molecules which combine serotonin transporter reuptake inhibition with serotonin (5-HT, such as 5-HT2A) receptor antagonism in one molecular entity. The serotonin-selective reuptake inhibitor (SSRI) homologue portion of the molecule shows an affinity to the serotonin reuptake transporter (SERT) and has antidepressant properties. The piperazine or piperidine portion of the molecule demonstrates an affinity to 5-HT receptors and restores the undesired side effects of SSRIs.


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