The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2011
Filed:
Jan. 10, 2007
Alexander Comely, Barcelona, ES;
Llorenç Rafecas Jane, Llorenç del Penedes, ES;
Nicolas Tesson, Barcelona, ES;
Antoni Riera Escale, Barcelona, ES;
Alexander Comely, Barcelona, ES;
Llorenç Rafecas Jane, Llorenç del Penedes, ES;
Nicolas Tesson, Barcelona, ES;
Antoni Riera Escale, Barcelona, ES;
Sinclair Pharmaceuticals Limited, Surrey, GB;
Abstract
It comprises a preparation process of delmopinol or a pharmaceutically acceptable salt and/or a solvate thereof, by submitting the compound of formula (II) where Rand Rare the same or different, independently selected from the group consisting of H, (C-C)-alkyl or, alternatively, Rand Rform, together with the carbon atom to which they are attached, a (C-C)-cycloalkyl radical; and Ris a radical selected from the group consisting of CF, (C-C)-alkyl, phenyl, and phenyl mono- or disubstituted by a radical selected from the group consisting of (C-C)-alkyl, halogen and nitro to a deprotection and cyclisation reaction. The process is useful to prepare delmopinol or its salts on an industrial scale. The compound of formula (II) is new and also forms part of the present invention, as well as its preparation process and other new intermediates of said preparation process.