The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2011
Filed:
Jun. 25, 2008
Magnus Nilsson, Huddinge, SE;
Lourdes Oden, Huddinge, SE;
Pia Kahnberg, Huddinge, SE;
Urszula Grabowska, Little Chesterford, GB;
Magnus Nilsson, Huddinge, SE;
Lourdes Oden, Huddinge, SE;
Pia Kahnberg, Huddinge, SE;
Urszula Grabowska, Little Chesterford, GB;
Medivir AB, Huddinge, SE;
Abstract
Compounds of the formula II: whereinRis the side chain of leucine, isoleucine, cyclohexylglycine, O-methyl threonine, 4-fluoroleucine or 3-methoxyvaline;Ris H, methyl or F;Rq is trifluoromethyl and Rq' is H or Rq and Rq′ define keto;Q is a p-(C-Calkylsulphonyl)phenyl- or an optionally substituted 4-(C-Calkyl)piperazin-1-yl-thiazol-4-yl- moiety have utility in the treatment of disorders characterized by inappropriate expression or activation of cathepsin K, such as osteoporosis, osteoarthritis, rheumatoid arthritis or bone metastases.