The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2011
Filed:
Nov. 29, 2002
Markus Pompejus, Freinsheim, DE;
Burkhard Kröger, Limburgerhof, DE;
Hartwig Schröder, Nussloch, DE;
Oskar Zelder, Speyer, DE;
Gregor Haberhauer, Limburgerhof, DE;
Stefan Haefner, Ludwigshafen, DE;
Corrinna Klopprogge, Ludwigshafen, DE;
Markus Pompejus, Freinsheim, DE;
Burkhard Kröger, Limburgerhof, DE;
Hartwig Schröder, Nussloch, DE;
Oskar Zelder, Speyer, DE;
Gregor Haberhauer, Limburgerhof, DE;
Stefan Haefner, Ludwigshafen, DE;
Corrinna Klopprogge, Ludwigshafen, DE;
Evonik Degussa GmbH, Essen, DE;
Abstract
Isolated nucleic acid molecules, which encode novel metabolic regulatory proteins fromare described. These nucleic acid molecules are involved in the biosynthesis of a fine chemical, e.g., methionine biosynthesis. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing metabolic regulatory nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides methods of producing methionine from microorganisms, e.g.,, which involve culturing recombinant microorganisms which overexpress or underexpress at least one metabolic regulatory molecule of the invention under conditions such that methionine is produced. Also featured are methods of producing a fine chemical, e.g., methionine, which involve culturing recombinant microorganisms having selected metabolic regulatory genes deleted or mutated under conditions such that the fine chemical, e.g., methionine, is produced.