The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2011
Filed:
May. 19, 2004
Edmund Hoppe, Krailling, DE;
Gisela Peraus, München, DE;
Jonathan Rothblatt, Somerville, MA (US);
Ekkehard Leberer, Germering, DE;
Luc Mercken, Saint Maur, FR;
Sylvie Dreisler, Verrières, FR;
Edmund Hoppe, Krailling, DE;
Gisela Peraus, München, DE;
Jonathan Rothblatt, Somerville, MA (US);
Ekkehard Leberer, Germering, DE;
Luc Mercken, Saint Maur, FR;
Sylvie Dreisler, Verrières, FR;
Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;
Abstract
The present invention relates to an improved process for determining γ-secretase activity and for detecting γ-secretase, a subunit protein of γ-secretase, or a γ-secretase-like proteinase. In particular, the present invention relates to processes for the identification of a γ-secretase or of a cDNA which codes for a γ-secretase, a subunit protein of γ-secretase, or a γ-secretase-like proteinase. Another embodiment of the present invention relates to processes for the identification of substances which can inhibit the activity of γ-secretase, or a γ-secretase-like proteinase.