The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 22, 2011

Filed:

Apr. 24, 2009
Applicants:

Andrew H.-j. Wang, Taipei, TW;

Kai-fa Huang, Taipei, TW;

Inventors:

Andrew H.-J. Wang, Taipei, TW;

Kai-Fa Huang, Taipei, TW;

Assignee:

Academia Sinica, Taipei, TW;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/00 (2006.01); C12N 9/10 (2006.01); C12N 9/86 (2006.01); C12P 21/06 (2006.01); G01N 31/00 (2006.01); G06F 19/00 (2006.01); G06G 7/48 (2006.01);
U.S. Cl.
CPC ...
Abstract

A crystalline structure of glutaminyl cyclase (QC) is described. Also described are the methods of preparing the crystalline structure of QC and the methods for identifying candidate inhibitors of QC. In addition, a structural basis for the rational design or identification of new inhibitors that may be used to treat QC-associated disorders is also described.


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