The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2011
Filed:
Aug. 13, 2002
Koichiro Ono, Gotenba, JP;
Toshihiko Ohtomo, Shizuoka, JP;
Masayuki Tsuchiya, Shizuoka, JP;
Yasushi Yoshimura, Gotenba, JP;
Yasuo Koishihara, Gotenba, JP;
Masaaki Kosaka, Tokushima, JP;
Koichiro Ono, Gotenba, JP;
Toshihiko Ohtomo, Shizuoka, JP;
Masayuki Tsuchiya, Shizuoka, JP;
Yasushi Yoshimura, Gotenba, JP;
Yasuo Koishihara, Gotenba, JP;
Masaaki Kosaka, Tokushima, JP;
Chugai Seiyako Kabushiki Kaisha, Tokyo, JP;
Abstract
The invention provides a reshaped human anti-HM 1.24 antibody having: (A) an L chain having (1) the C region of a human L chain, and (2) the V region of an L chain having the FR of a human L chain and the CDR of the L chain of a mouse anti-HM 1.24 monoclonal antibody; and (B) an H chain having (1) the C region of a human H chain, and (2) the V region of an H chain having the FR of a human H chain and the CDR of the H chain of a mouse anti-HM 1.24 monoclonal antibody. This reshaped human antibody is derived from human antibody and the CDR has a low antigenicity, and the reshaped human antibody of the present invention has a low antigenicity and can be used for medical treatment.