The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2011

Filed:

Jul. 11, 2006
Applicants:

Tae Hee Ha, Suwon-si, KR;

Won Jeong Kim, Suwon-si, KR;

Hee Sook OH, Seoul, KR;

Chang Hee Park, Yongin-si, KR;

Jae Chul Lee, Suwon-si, KR;

Han Kyong Kim, Yongin-si, KR;

Kwee-hyun Suh, Suwon-si, KR;

Inventors:

Tae Hee Ha, Suwon-si, KR;

Won Jeong Kim, Suwon-si, KR;

Hee Sook Oh, Seoul, KR;

Chang Hee Park, Yongin-si, KR;

Jae Chul Lee, Suwon-si, KR;

Han Kyong Kim, Yongin-si, KR;

Kwee-Hyun Suh, Suwon-si, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

Optically pure esomeprazole and its salt can be simply prepared by dissolving (S)-(−)-binol, a weak base and the racemic form of omeprazole in a mixture of a water-compatible organic solvent and water at a high temperature, cooling the mixed solution to crystallize the inclusion complex of esomeprazole and (S)-(−)-binol, and removing the (S)-(−)-binol moiety from the crystallized inclusion complex.


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