The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2011

Filed:

Mar. 26, 2004
Applicants:

J. Yun Tso, Menlo Park, CA (US);

Anton Wellstein, Washington, DC (US);

Debra Chao, Fremont, CA (US);

Inventors:

J. Yun Tso, Menlo Park, CA (US);

Anton Wellstein, Washington, DC (US);

Debra Chao, Fremont, CA (US);

Assignee:

Georgetown University, Washington, DC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/22 (2006.01); C07K 16/30 (2006.01); C12N 5/20 (2006.01); C12P 21/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention concerns antibodies that neutralize at least one biological activity of pleiotrophin. The antibodies can inhibit cancer cell growth and angiogenesis in vitro or in vivo. The present invention provides for methods of inhibiting cancer cell growth or angiogenesis in a subject comprising administering to said subject an effective amount of the antibodies described herein. The present invention also provides for methods of making the neutralizing antibodies described herein.


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