The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2011

Filed:

Jun. 13, 2006
Applicants:

Jingwu Duan, Yardley, PA (US);

Zhonghui LU, King of Prussia, PA (US);

David S. Weinstein, East Windsor, NJ (US);

Bin Jiang, Norristown, PA (US);

Inventors:

Jingwu Duan, Yardley, PA (US);

Zhonghui Lu, King of Prussia, PA (US);

David S. Weinstein, East Windsor, NJ (US);

Bin Jiang, Norristown, PA (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 231/56 (2006.01); A01N 43/56 (2006.01);
U.S. Cl.
CPC ...
Abstract

Non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-κB activity including obesity, diabetes, inflammatory and immune diseases, and have the structure of formula (I) or an enantiomer, a diastereomer, a pharmaceutically acceptable salt, or hydrate thereof, where J is selected from NRor C(R)(R); K is selected from NRor C(R)(R); L is selected from NRor C(R)(R); and A, X, Y, R, R, R, R, R, R, R, R, R, R, R, R, and n are defined herein. Also provided are pharmaceutical compositions and methods of treating obesity, diabetes and inflammatory or immune associated diseases comprising said compounds.


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