The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2011
Filed:
Jul. 05, 2006
Xiao-xiong Zhou, Huddinge, SE;
Christer Sahlberg, Huddinge, SE;
Xiao-Xiong Zhou, Huddinge, SE;
Christer Sahlberg, Huddinge, SE;
Medivir AB, Huddinge, SE;
Abstract
Compounds of the formula (I) wherein: Ris independently H—OR, —NHR; C-Calkyl; or, when n is 2, adjacent Rtogether define an olefinic bond; Ris H; or when the gem Ris C-Calkyl, that Rmay also be C-Calkyl; or when the gem Ris —OR, that Rmay also be —C(═O)OH or a pharmaceutically acceptable ester thereof; Ris independently H, or a pharmaceutically acceptable ester thereof; Ris independently H or a pharmaceutically acceptable amide thereof; Rand R6 are H or an amine prodrug moiety n is 1, 2 or 3; and pharmaceutically acceptable salts thereof; have utility in the treatment or prophylaxis of HIV, especially reverse transcriptase mutants which allow an obligate chain terminating nucleoside- or nucleotide phosphate to be excised from the nascent DNA strand by ATP- or pyrophosphate-mediated excision.