The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2011
Filed:
Aug. 11, 2010
Ze′ev A. Ronai, San Diego, CA (US);
Anindita Bhoumik, San Diego, CA (US);
Nicholas D. P. Cosford, San Diego, CA (US);
Russell Dahl, Carlsbad, CA (US);
Ze′ev A. Ronai, San Diego, CA (US);
Anindita Bhoumik, San Diego, CA (US);
Nicholas D. P. Cosford, San Diego, CA (US);
Russell Dahl, Carlsbad, CA (US);
Burnham Institute for Medical Research, La Jolla, CA (US);
Abstract
There are provided methods of inhibiting growth and metastasis of melanoma, methods of sensitizing melanoma cells to apoptosis, and methods of treating a subject having melanoma using acetyl isogambogic acid, celastrol, or a derivative thereof. There are further provided derivatives of celastrol and compositions comprising acetyl isogambogic acid, celastrol, or a derivative thereof.