The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2011

Filed:

Jan. 18, 2007
Applicants:

Karl Schoenafinger, Alzenau, DE;

Gerhard Jaehne, Frankfurt, DE;

Elisabeth Defossa, Idstein, DE;

Lothar Schwink, Stadtallendorf, DE;

Holger Wagner, Biberach/Mettenberg, DE;

Christian Buning, Bonn, DE;

Georg Tschank, Essenheim, DE;

Ulrich Werner, Miehlen, DE;

Inventors:

Karl Schoenafinger, Alzenau, DE;

Gerhard Jaehne, Frankfurt, DE;

Elisabeth Defossa, Idstein, DE;

Lothar Schwink, Stadtallendorf, DE;

Holger Wagner, Biberach/Mettenberg, DE;

Christian Buning, Bonn, DE;

Georg Tschank, Essenheim, DE;

Ulrich Werner, Miehlen, DE;

Assignee:

Sanofi-A Ventis Deutschland GmbH, Frankfurt am Main, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); A61K 31/522 (2006.01); A61P 3/06 (2006.01); A61P 3/10 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention involves substituted bicyclic 8-pyrrolidinoxanthines and their derivatives of formula I: wherein the various R groups are defined herein. The present invention also comprises pharmaceutical compositions comprising them as well as processes for the preparation of these compounds and methods for the treatment of metabolic disorders such as type-2 diabetes, insulin resistance, hyperglycemia, arteriosclerosis diseases and the like through the administration of said compositions.


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