The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2011

Filed:

Jul. 01, 2004
Applicants:

Claudio Vita, Gif sur Yvette, FR;

Mireille Sauvage-vita, Legal Representative, Gif sur Yvette, FR;

Fabio Vita, Legal Representative, Gif sur Yvette, FR;

Elena Vita, Legal Representative, Gif sur Yvette, FR;

Loïc Le Clainche, Paris, FR;

Véronique Monjardet, Paris, FR;

Inventors:

Claudio Vita, Gif sur Yvette, FR;

Mireille Sauvage-Vita, legal representative, Gif sur Yvette, FR;

Fabio Vita, legal representative, Gif sur Yvette, FR;

Elena Vita, legal representative, Gif sur Yvette, FR;

Loïc Le Clainche, Paris, FR;

Véronique Monjardet, Paris, FR;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 31/555 (2006.01); A01N 55/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention concerns uranium-chelating peptides as well as their uses for decontaminating soils and water, and for detecting and treating people contaminated by uranium. Said peptides have a helix-loop-helix type structure comprising the sequence of a calmodulin loop including at least one mutation of neutral residues selected from the group consisting of S, T, C, H, Y, N and Q, of one, two or three residues of at least one of the four calmodulin calcium binding sites: site I: residues selected among D20, D22 and D24 residues; site II: residues selected among D56, D58 and N60 residues; site III: residues selected among D93, D95 and N97 residues; site IV: residues selected among D129, D131 and D133 residues; said positions being indicated with reference to the human calmodulin sequence.


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