The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2011
Filed:
Mar. 04, 2008
James F. Hainfeld, Shoreham, NY (US);
Wenqiu Liu, Dix Hills, NY (US);
Richard D. Powell, Raleigh, NC (US);
Vishwas N. Joshi, East Setauket, NY (US);
James F. Hainfeld, Shoreham, NY (US);
Wenqiu Liu, Dix Hills, NY (US);
Richard D. Powell, Raleigh, NC (US);
Vishwas N. Joshi, East Setauket, NY (US);
Nanoprobes, Inc., Yaphank, NY (US);
Abstract
Disclosed embodiments concern site-specific, enzymatic-directed deposition of elemental metal for in-situ analysis. Enzyme substrates are contacted with metal ions and subsequently direct the deposition of elemental metals. Sensitive and selective detection of target molecules, such as biomarkers in various biological samples, can be obtained using various methods, such as in-situ chromogenic immunohistochemical (IHC) detection with bright field light microscopy.