The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2011
Filed:
Dec. 09, 2008
Bradley Mccoll, London, GB;
Megan E. Baldwin, Brighton East, AU;
Stephen A. Stacker, Balwyn North, AU;
Marc G. Achen, North Melbourne, AU;
Bradley McColl, London, GB;
Megan E. Baldwin, Brighton East, AU;
Stephen A. Stacker, Balwyn North, AU;
Marc G. Achen, North Melbourne, AU;
Vegenics Limited, Toorak Victoria, AU;
Abstract
Methods for activating endothelial growth factors VEGF-C or VEGF-D with plasmin, and methods of treatment comprising administering a pharmaceutical compositions comprising plasmin. Also disclosed are methods of screening for inhibitors of activation of the growth factors by plasmin, and method of treatment by blocking activation of VEGF-C/D activation by plasmin. Further disclosed are methods for screening for other proteases that activate VEGF-CD, and for inhibitors of such activation. The invention further includes inhibitors of plasmin activity and methods of treating patients in need thereof with said inhibitors.