The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2011
Filed:
Jun. 25, 2007
Tatsuya Okuzumi, Kawasaki, JP;
Kazuyuki Sagi, Kawasaki, JP;
Toshihiko Yoshimura, Kawasaki, JP;
Yuji Tanaka, Kawasaki, JP;
Eiji Nakanishi, Kawasaki, JP;
Miho Ono, Kawasaki, JP;
Masahiro Murata, Kawasaki, JP;
Tatsuya Okuzumi, Kawasaki, JP;
Kazuyuki Sagi, Kawasaki, JP;
Toshihiko Yoshimura, Kawasaki, JP;
Yuji Tanaka, Kawasaki, JP;
Eiji Nakanishi, Kawasaki, JP;
Miho Ono, Kawasaki, JP;
Masahiro Murata, Kawasaki, JP;
Ajinomoto Co., Inc., Tokyo, JP;
Abstract
Phenylalanine derivatives of the following formula, analogues thereof and pharmaceutically acceptable salts thereof have an antagonistic activity to α4 integrin. They are used as therapeutic agents or preventive agents for various diseases concerning α4 integrin in which α4 integrin-depending adhesion process participates in the pathology, such as inflammatory diseases, rheumatoid arthritis, inflammatory bowel diseases, systemic lupus erythematosus, multiple sclerosis, Sjögren's syndrome, asthma, psoriasis, allergy, diabetes, cardiovascular diseases, arterial sclerosis, restenosis, tumor proliferation, tumor metastasis and transplantation rejection. wherein R1 is a methyl group and R2 is a methoxy group.