The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 08, 2011

Filed:

Jun. 11, 2007
Applicants:

Mohammed Abdul Raheem, Brantford, CA;

Zhi-xian Wang, Brantford, CA;

Eckardt C. G. Wolf, Brantford, CA;

Inventors:

Mohammed Abdul Raheem, Brantford, CA;

Zhi-Xian Wang, Brantford, CA;

Eckardt C. G. Wolf, Brantford, CA;

Assignee:

Apotex Pharmachem Inc., Brantford, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4172 (2006.01); C07D 233/64 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to a process for the preparation of an aminoalkyl phenyl carbamate compound of formula 1, wherein Rand Rindependently are hydrogen or Calkyl; Rand Rare the same or different and each is a lower alkyl; or Rand Rtogether with the nitrogen to which they are attached form a cyclic moiety of a three to eight-member ring, with or without a hetero atom like nitrogen or oxygen; Rand Rindependently are hydrogen, linear, branched or cyclic Calkyl, allyl, propargyl or benzyl; or Rand Rtogether with the nitrogen to which they are attached form a cyclic moiety of three to eight member ring, with or without a hetero atom like nitrogen or oxygen; the carbon center marked with '*' is racemic or enantiomerically enriched (R)- or (S)-configuration; and pharmaceutically acceptable addition salts, and crystalline and amorphous forms thereof comprising the steps of:


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