The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2011
Filed:
Dec. 24, 2004
Applicant:
Naoyoshi Yamada, Kasatsu, JP;
Inventor:
Naoyoshi Yamada, Kasatsu, JP;
Assignee:
Nippon Shinyaku Co., Ltd., Kyoto, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4425 (2006.01); C07D 213/56 (2006.01);
U.S. Cl.
CPC ...
Abstract
It is an object of the invention to provide a novel octahydronaphthalene derivative with an activity of inhibiting ICAM-4 expression and a pharmaceutically acceptable salt thereof. The invention encompasses, for example, agents for suppressing ICAM-1, therapeutic agents for inflammatory diseases, therapeutic agents for rheumatoid arthritis, immunosuppressive agents, and agents for suppressing cell growth, comprising N-(pyridin-3-ylmethyl)-(2E,4E)-5-[(1S,2S,4aR,6R,7S,8S,8aS)-7-hydroxy-2,6,8-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]-2-methylpenta-2,4-dienamide as an active ingredient.