The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 01, 2011

Filed:

Dec. 11, 2007
Applicants:

Iyassu K. Sebhat, Jersey City, NJ (US);

Michael Man-chu Lo, Edison, NJ (US);

Ravi P. Nargund, East Brunswick, NJ (US);

Amjad Ali, Freehold, NJ (US);

Chris Franklin, Keasbey, NJ (US);

Nicoletta Almirante, Milan, IT;

Laura Storoni, Cesano Maderno, IT;

Silvia Stefanini, San Donato Milanese, IT;

Inventors:

Iyassu K. Sebhat, Jersey City, NJ (US);

Michael Man-chu Lo, Edison, NJ (US);

Ravi P. Nargund, East Brunswick, NJ (US);

Amjad Ali, Freehold, NJ (US);

Chris Franklin, Keasbey, NJ (US);

Nicoletta Almirante, Milan, IT;

Laura Storoni, Cesano Maderno, IT;

Silvia Stefanini, San Donato Milanese, IT;

Assignees:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

NiCox S.A., Valbonne, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 257/00 (2006.01); C07D 403/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound having the structure wherein R is an angiotensin receptor antagonist active group, Y is -Y-Y-Y-Y-Y-; Yis C(RR); Ris selected from the group consisting of hydrogen and Calkyl; Ris selected from the group consisting of hydrogen, Calkyl, and —OC(O)Calkyl; Yis O or CH; Yis C(O) or CH; Yis O or CH; Yis —(CH)—(X)—(CH)— or is absent; X is —O— or —CRR—; and Rand Rare independently selected from the group consisting of hydrogen and C-Calkyl; or a pharmaceutically acceptable salt or hydrate thereof, which is useful for treating hypertension.


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