The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2011
Filed:
Jan. 19, 2006
Kenneth F. Buechler, Rancho Santa Fe, CA (US);
Mariusz G. Banaszczyk, San Marcos, CA (US);
Joseph Barry Noar, Solana Beach, CA (US);
Violeta Dinauer, San Diego, CA (US);
Kenneth F. Buechler, Rancho Santa Fe, CA (US);
Mariusz G. Banaszczyk, San Marcos, CA (US);
Joseph Barry Noar, Solana Beach, CA (US);
Violeta Dinauer, San Diego, CA (US);
Alere International, Waltham, MA (US);
Abstract
The present invention relates to novel arginine analogs, and methods for their synthesis and use. Such analogs are designed to provide a protected or free thiol (—SH) group, thereby providing a convenient linkage chemistry for coupling to a suitable group on a target such as a protein, polypeptide, detectable label or solid phase, and at a site distal to the guanidino group. Arginine analog conjugates are useful for generating antibodies that can bind specifically with dimethylarginine, which can be detected using such antibodies in immunoassays.