The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 01, 2011

Filed:

Aug. 08, 2006
Applicants:

Meng-hsin Chen, Westfield, NJ (US);

James B. Doherty, Montvale, NJ (US);

Robert Tynebor, Hatfield, PA (US);

Swaminathan R. Natarajan, Scotch Plains, NJ (US);

Zhen LI, Scotch Plains, NJ (US);

Soumya P. Sahoo, Old Bridge, NJ (US);

Inventors:

Meng-Hsin Chen, Westfield, NJ (US);

James B. Doherty, Montvale, NJ (US);

Robert Tynebor, Hatfield, PA (US);

Swaminathan R. Natarajan, Scotch Plains, NJ (US);

Zhen Li, Scotch Plains, NJ (US);

Soumya P. Sahoo, Old Bridge, NJ (US);

Assignee:

Merk Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4375 (2006.01); C07D 455/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds described by the chemical formula (I) or pharmaceutically acceptable salts thereof: (I) are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other arthritic conditions; inflamed joints, eczema, psoriasis or other inflammatory skin conditions such as sunburn; inflammatory eye conditions including conjunctivitis; pyresis, pain and other conditions associated with inflammation.


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