The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2011
Filed:
Dec. 25, 2006
Takayuki Inoue, Chuo-ku, JP;
Akira Tanaka, Chuo-ku, JP;
Kazuo Nakai, Chuo-ku, JP;
Hiroshi Sasaki, Chuo-ku, JP;
Fumie Takahashi, Chuo-ku, JP;
Shohei Shirakami, Chuo-ku, JP;
Keiko Hatanaka, Chuo-ku, JP;
Yutaka Nakajima, Chuo-ku, JP;
Koichiro Mukoyoshi, Chuo-ku, JP;
Hisao Hamaguchi, Chuo-ku, JP;
Shigeki Kunikawa, Chuo-ku, JP;
Yasuyuki Higashi, Chuo-ku, JP;
Takayuki Inoue, Chuo-ku, JP;
Akira Tanaka, Chuo-ku, JP;
Kazuo Nakai, Chuo-ku, JP;
Hiroshi Sasaki, Chuo-ku, JP;
Fumie Takahashi, Chuo-ku, JP;
Shohei Shirakami, Chuo-ku, JP;
Keiko Hatanaka, Chuo-ku, JP;
Yutaka Nakajima, Chuo-ku, JP;
Koichiro Mukoyoshi, Chuo-ku, JP;
Hisao Hamaguchi, Chuo-ku, JP;
Shigeki Kunikawa, Chuo-ku, JP;
Yasuyuki Higashi, Chuo-ku, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
The present invention provides a compound of formula (I) having an excellent JAK3 inhibition activity and being useful as an active ingredient of an agent for treating and/or preventing various immune diseases including autoimmune diseases inflammatory diseases, and allergic diseases. The compound according to the present invention has an inhibition activity against JAK3 and is thus useful as an active ingredient of an agent for treating or preventing diseases caused by undesirable cytokine signal transmission (e.g., rejection during organ/tissue transplantation, autoimmune diseases, multiple sclerosis, rheumatoid arthritis, psoriasis, asthma, atopic dermatitis, Alzheimer's disease, and atherosclerotic disease), or diseases caused by abnormal cytokine signal transmission (e.g., cancer and leukemia).