The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2011
Filed:
Jul. 19, 2005
Balasingam Radhakrishnan, Chapel Hill, NC (US);
Diti Aggarwal, Raleigh, NC (US);
Michelle Ferro, Raleigh, NC (US);
Kenneth D. James, Mebane, NC (US);
Navdeep B. Malkar, Cary, NC (US);
Mark A. Miller, Raleigh, NC (US);
Monica Puskas, Spring Hope, NC (US);
Nnochiri N. Ekwuribe, Cary, NC (US);
Balasingam Radhakrishnan, Chapel Hill, NC (US);
Diti Aggarwal, Raleigh, NC (US);
Michelle Ferro, Raleigh, NC (US);
Kenneth D. James, Mebane, NC (US);
Navdeep B. Malkar, Cary, NC (US);
Mark A. Miller, Raleigh, NC (US);
Monica Puskas, Spring Hope, NC (US);
Nnochiri N. Ekwuribe, Cary, NC (US);
Biocon Limited, , IN;
Abstract
The invention provides a complex including a cation and an insulin compound conjugate. The insulin compound conjugate includes insulin compound, such as human insulin or an analog thereof, conjugated to a modifying moiety, such as a polyethylene glycol moiety. The invention also includes solids and pharmaceutical compositions including such complexes, methods of making such complexes, and methods of using such complexes in the treatment of insulin compound deficiencies and other ailments. Further, the invention includes novel insulin compound conjugates and modifying moieties for use in making novel insulin compound conjugates. The invention also includes fatty acid compositions for administration of pharmaceutical agents, such as the novel insulin compound conjugates, and/or the cation-insulin compound conjugate complexes of the invention.