The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2011
Filed:
Mar. 23, 2010
Douglas T. Gjerde, Saratoga, CA (US);
Allen Burge, Sunnyvale, CA (US);
Ronald Jones, Morgan Hill, CA (US);
Mark Abel, San Jose, CA (US);
Douglas T. Gjerde, Saratoga, CA (US);
Allen Burge, Sunnyvale, CA (US);
Ronald Jones, Morgan Hill, CA (US);
Mark Abel, San Jose, CA (US);
PhyNexus, Inc., San Jose, CA (US);
Abstract
The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a bed of extraction media positioned in the column, often between two frits. In some embodiments, the extraction columns employ modified pipette tips as column bodies. In some embodiments, the extraction columns are comprised of frits having a low pore. In some embodiments, the frits of the extraction columns have a pore volume of less than one microliter or less than 10% of the interstitial volume of the bed of extraction media.