The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2011
Filed:
Sep. 14, 2007
Per Artur Sven Artursson, Uppsala, SE;
Mohamed Mahmoud Issa, Uppsala, SE;
Sabina Prochazkova Strand, Tiller, NO;
Kjell Morten Varum, Trondheim, NO;
Per Artur Sven Artursson, Uppsala, SE;
Mohamed Mahmoud Issa, Uppsala, SE;
Sabina Prochazkova Strand, Tiller, NO;
Kjell Morten Varum, Trondheim, NO;
FMC Biopolymer AS, Drammen, NO;
Abstract
Low molecular weight low molecular weight chitosan oligomers were able to self-assemble siRNA into nanosized particles, provide protection against enzymatic degradation, and mediate gene silencing that is stable over a long period of time in vitro. The control of structural variables in formulating complexes of siRNA with low molecular weight chitosans provides an efficient alternative delivery system for siRNA in vitro and in vivo.