The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2011
Filed:
Jun. 27, 2007
Priscilla Reyes, Duncan, OK (US);
William F. Moore, Bloomington, IN (US);
Randy Joe Myers, Bloomington, IN (US);
Patrick H. Ruane, Hayward, CA (US);
Melinda S. Morrell, Vienna, VA (US);
Priscilla Reyes, Duncan, OK (US);
William F. Moore, Bloomington, IN (US);
Randy Joe Myers, Bloomington, IN (US);
Patrick H. Ruane, Hayward, CA (US);
Melinda S. Morrell, Vienna, VA (US);
Cook Incorporated, Bloomington, IN (US);
Med Institute, Inc., West Lafayette, IN (US);
Abstract
This disclosure relates to endolumenal medical devices coated with a taxane therapeutic agent in one or more solid form(s) having varying dissolution rates. Particularly preferred coatings comprise amorphous paclitaxel, dihydrate paclitaxel, or combinations thereof that provide durable coatings that release paclitaxel over a desired period of time, which can be on the order of hours, days or weeks. Preferred embodiments relate to medical device coatings of paclitaxel, or paclitaxel analogs or derivatives, having one or more polymorph solid forms that provide a prolonged release of paclitaxel within a body vessel without requiring a polymer carrier or barrier layer to achieve the desired rate of paclitaxel elution.