The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2011
Filed:
Dec. 03, 2007
Suke Wang, Edison, NJ (US);
Frederick James Monsma, Jr., Summit, NJ (US);
Xiaoxin Yang, Livingston, NJ (US);
Eric L. Gustafson, Annandale, NJ (US);
Maureen Laverty, Old Bridge, NJ (US);
Elizabeth B. Smith, Princeton, NJ (US);
Suke Wang, Edison, NJ (US);
Frederick James Monsma, Jr., Summit, NJ (US);
Xiaoxin Yang, Livingston, NJ (US);
Eric L. Gustafson, Annandale, NJ (US);
Maureen Laverty, Old Bridge, NJ (US);
Elizabeth B. Smith, Princeton, NJ (US);
Schering Corporation, Kenilworth, NJ (US);
Abstract
The invention relates to the use of the interaction between the GPR78 polypeptide or the GPR26 polypeptide and their identified ligands and antagonists as the basis for screening methods for the identification of agents that modulate the activity of these receptors, and for diagnostic and therapeutic purposes. The agents identified by the screening methods of the invention have use in the treatment of GPR78- and/or GPR26-mediated disorders, including, but not limited to, neurological disorders (such as anxiety disorders), metabolic disorders, cardiovascular disorders, hormone-related disorders, vascular disorders and hyperproliferative disorders (such as cancer).