The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 18, 2011

Filed:

Apr. 05, 2007
Applicants:

John J. Baldwin, Gwynedd Valley, PA (US);

David A. Claremon, Maple Glen, PA (US);

Colin M. Tice, Ambler, PA (US);

Salvacion Cacatian, Blue Bell, PA (US);

Lawrence W. Dillard, Yardley, PA (US);

Alexey V. Ishchenko, Somerville, MA (US);

Jing Yuan, Lansdale, PA (US);

Zhenrong Xu, Horsham, PA (US);

Gerard Mcgeehan, Garnet Valley, PA (US);

Wei Zhao, Eagleville, PA (US);

Robert D. Simpson, Wilmington, DE (US);

Suresh B. Singh, Kendall Park, NJ (US);

Patrick T. Flaherty, Pittsburgh, PA (US);

Inventors:

John J. Baldwin, Gwynedd Valley, PA (US);

David A. Claremon, Maple Glen, PA (US);

Colin M. Tice, Ambler, PA (US);

Salvacion Cacatian, Blue Bell, PA (US);

Lawrence W. Dillard, Yardley, PA (US);

Alexey V. Ishchenko, Somerville, MA (US);

Jing Yuan, Lansdale, PA (US);

Zhenrong Xu, Horsham, PA (US);

Gerard McGeehan, Garnet Valley, PA (US);

Wei Zhao, Eagleville, PA (US);

Robert D. Simpson, Wilmington, DE (US);

Suresh B. Singh, Kendall Park, NJ (US);

Patrick T. Flaherty, Pittsburgh, PA (US);

Assignee:

Vitae Pharmaceuticals, Inc., Fort Washington, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 211/22 (2006.01); A61K 31/445 (2006.01);
U.S. Cl.
CPC ...
Abstract

Described are diaminopropanols of which are orally active and bind to renin to inhibit its activity. They are useful in the treatment or amelioration of diseases associated with elevated. levels of renin activity or in the treatment of aspartic protease mediated disorders. Also described is a method for the use of the diaminopropanols in ameliorating or treating renin related disorders in a subject in need thereof.


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