The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2011
Filed:
Jun. 22, 2007
Motohide Satoh, Takatsuki, JP;
Hisateru Aramaki, Takatsuki, JP;
Masaki Yamashita, Takatsuki, JP;
Masafumi Inoue, Takatsuki, JP;
Hiroshi Kawakami, Takatsuki, JP;
Hisashi Shinkai, Takatsuki, JP;
Hiroshi Nakamura, Takatsuki, JP;
Yuji Matsuzaki, Takatsuki, JP;
Shuichi Wamaki, Takatsuki, JP;
Motohide Satoh, Takatsuki, JP;
Hisateru Aramaki, Takatsuki, JP;
Masaki Yamashita, Takatsuki, JP;
Masafumi Inoue, Takatsuki, JP;
Hiroshi Kawakami, Takatsuki, JP;
Hisashi Shinkai, Takatsuki, JP;
Hiroshi Nakamura, Takatsuki, JP;
Yuji Matsuzaki, Takatsuki, JP;
Shuichi Wamaki, Takatsuki, JP;
Japan Tobacco Inc., Tokyo, JP;
Abstract
The present invention relates to a compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof, or a solvate thereof, and a pharmaceutical composition, an anti-HIV agent and an HIV integrase inhibitor containing such compound. The compound of the present invention has an HIV integrase inhibitory activity, and is useful as an anti-HIV agent, or as an agent for the prophylaxis or treatment of AIDS. In addition, by the combined use with other anti-HIV agents such as a protease inhibitor, a reverse transcriptase inhibitor and the like, it can be a more effective anti-HIV agent. Because it shows integrase-specific high inhibitory activity, the compound can be a pharmaceutical agent safe on human body, which causes only a fewer side effects.