The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 18, 2011

Filed:

Jun. 30, 2006
Applicants:

Chise Mukaidani, Higashihiroshima, JP;

Katsutoshi Yoshizato, Higashihiroshima, JP;

Norio Masumoto, Higashihiroshima, JP;

Miho Kataoka, Kumamoto, JP;

Tatsuhiko Tsunoda, Yokohama, JP;

Fuyuki Miya, Yokohama, JP;

Inventors:

Chise Mukaidani, Higashihiroshima, JP;

Katsutoshi Yoshizato, Higashihiroshima, JP;

Norio Masumoto, Higashihiroshima, JP;

Miho Kataoka, Kumamoto, JP;

Tatsuhiko Tsunoda, Yokohama, JP;

Fuyuki Miya, Yokohama, JP;

Assignees:

Hiroshima Industrial Promotion Organization, Hiroshima, JP;

Biointegrence Inc., Hiroshima, JP;

Riken, Saitama, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/08 (2006.01); A01N 63/00 (2006.01); A61K 38/27 (2006.01);
U.S. Cl.
CPC ...
Abstract

Human adult hepatocytes are transplanted into an immunodeficient hepatopathy mouse and then human growth hormone is administered to the mouse to thereby elevate twice or more the replacement ratio by the human adult hepatocytes having been transplanted. Further, human growth hormone is administered to an immunodeficient hepatopathy mouse carrying human young hepatocytes transplanted thereinto so as to improve fatty liver of the mouse in which about 70% or more of the hepatocytes have been replaced by the human hepatocytes.


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