The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2011
Filed:
Apr. 07, 2005
YE Fang, Painted Post, NY (US);
Ann M. Ferrie, Painted Post, NY (US);
Norman H. Fontaine, Painted Post, NY (US);
Anthony G. Frutos, Painted Post, NY (US);
Eric J. Mozdy, Elmira, NY (US);
Chuan-che Wang, Ithaca, NY (US);
Po Ki Yuen, Corning, NY (US);
Ye Fang, Painted Post, NY (US);
Ann M. Ferrie, Painted Post, NY (US);
Norman H. Fontaine, Painted Post, NY (US);
Anthony G. Frutos, Painted Post, NY (US);
Eric J. Mozdy, Elmira, NY (US);
Chuan-Che Wang, Ithaca, NY (US);
Po Ki Yuen, Corning, NY (US);
Corning Incorporated, Corning, NY (US);
Abstract
The present invention includes several methods for modifying the current processes of manufacturing optical sensing microplates that use continuous waveguide films to reduce/eliminate crosstalk between the biosensors that are incorporated within wells. The methods include (1) physically deteriorating/removing the waveguide film between individual biosensors; (2) chemically depositing highly absorbing materials within the waveguide film between individual biosensors; (3) patterning disordered (scattering) regions between the diffraction gratings that define individual biosensors; (4) using a specific mask and depositing individual patches of waveguide film, where each patch defines at least one biosensor. Each of these methods and several other methods described herein prevent the propagation of light between individual sensing regions, thereby eliminating optical crosstalk between the biosensors. The present invention also includes the resulting microplate.